Tramadol is a centrally acting analgesic, which possesses opioid agonist properties and activates The cytochrome P-450 (CYP450) system (CYP2D6 and CYP3A4 enzymes) appears to be much involved in . 1–5 mg/kg PO q.8–12 h We use cookies to help provide and enhance our service and tailor content...